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In cell and tissue models, Epithalon upregulates telomerase activity, maintains telomere length, and modulates aging-related gene expression (p16, p21) to delay senescence

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Therefore, future experimental models and human studies should explore in depth the specific mechanism of action of acupuncture on pathological changes in Tau and how this traditional medical technique can be effectively utilized to treat or prevent TBI-induced neurodegenerative diseases (Liu, 2023)

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