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10.1371/journal.pone.0054794 58 WesterfieldM

BMAL1 forms heterodimers with CLOCK to drive the transcription of core clock-controlled genes such as PERS, CRYS and DBP (Mendoza-Viveros et al., 2017), and consistently, HRD1 overexpression significantly reduces PER1 and DBP mRNA levels, suggesting downstream transcriptional suppression via BMAL1 destabilization (Guo et al., 2020)

The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer

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