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Interestingly, administration of the l-theaninecaffeine combination was associated with a significant decrease in reactivity of CEN compared to placebo in a cluster that included the bilateral middle and superior frontal, paracingulate and precentral gyri and the left inferior frontal gyrus (p = 0.007)

Cleaned FASP eluates were evaporated completely in SpeedVac concentrator (Thermo Fisher Scientific) and transferred into LC-MS vial containing PEG (final concentration 0.001%, v/v) using 25 l of 50% acetonitrile (ACN) with 2.5% formic acid (FA) and 100 l of ACN

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