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KPV targets anti-inflammatory conditions including IBD, colitis, dermatitis, and bronchial inflammation

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[1] Unlike the folic acid derivative leucovorin, folic acid is not clinically useful in offsetting the action of folate reductase inhibitors because it requires the enzyme dihydrofolate reductase for activation

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Mechanisms (Preclinical Only) Rodent and in vitro studies report modulation of the nitric oxide system via SrcCaveolin1eNOS signaling and context dependent effects on vascular tone