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Interestingly, high GPX1 and GPX4 expression are correlated to poor prognosis in patients suffering AML, suggesting that targeting one or both proteins could be of high potential therapeutic value [36]

2 AKI and mitochondrial energy metabolism 2.1 Basic structure and functions of mitochondria Mitochondria are dynamic, double-membraned organelles typically exhibiting an ellipsoidal or rod-shaped morphology

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