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doi: 10.3389/fpsyt.2025.1569826 Received 01 February 2025 Accepted 16 July 2025 Published 19 August 2025 Volume 16 - 2025 Edited by Sandra Moreno, Roma Tre University, Italy Reviewed by Poonam Chanderlal Sharma, University of Mississippi Medical Center, United States Ashish Patil, Roche, United States Updates Copyright 2025 Han, Almeida, Anand, Salloum, Kanaan, Gadad and Daher

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Why 90% of clinical drug development fails and how to improve it