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The analytical workflow involves initial measurement of peptide mass-to-charge ratios (m/z) in MS1 scans, followed by fragmentation of selected peptides to produce tandem mass spectra (MS/MS) containing sequence information, which are subsequently matched against protein databases for identification (Nimer and Abdel Rahman, 2023)

61 HuangY.ZhouZ.ZhangJ.HaoZ.HeY.WuZ.et al (2021b)

Apoferritin improves motor deficits in MPTP-treated mice by regulating brain iron metabolism and ferroptosis

Myricitrin attenuates high glucose-induced apoptosis through activating akt-nrf2 signaling in H9c2 cardiomyocytes

These signals drive serine phosphorylation of the insulin receptor substrate IRS1, thereby blocking insulin signal transduction and contributing to insulin resistance (McLaughlin et al., 2017)