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Acetylcarnitine can also improve mitochondrial biosynthesis, quality control and dynamics by increasing the levels of peroxisome proliferator-activated receptor coactivator 1 (PGC-1) and mitochondrial DNA (mtDNA) [16]
[122] demonstrated that carnitine worsened the recovery of contractile function in transient ischemia
Mayo Clinic proceedings , 88 6, 544-51
TsokoMBeauseigneurFGrestiJNiotIDemarquoyJBoichotJet al
The plasmid DNA was linearised with the restriction enzyme Spe1 (New England BioLabs, Inc) and transcribed into mRNA by T7 RNA polymerase with the AMBION mMESSAGE mMACHINE TM T7 transcription kit (Invitrogen TM , Thermo Fisher Scientific)
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