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In contrast, cells with lower senescence burden may have less FOXO4p53 dependence, or may buffer p53 relocalization through other regulators, which might explain the limited apoptosis in younger cultures compared to aged cell cultures

78 A statistical analysis that included nine randomized controlled trials, involving a total of 591 women with PCOS, also reported finding omega-3 fatty acid supplementation improved insulin sensitivity, lowered total cholesterol and triglyceride levels, and raised levels of adiponectin (a signaling peptide primarily produced by fat tissue that improves insulin sensitivity and has anti-inflammatory properties)

277 Researchers have synthesized ILs, such as DLin-KC2-DMA and DLin-MC3-DMA, with the latter used as a novel component for encapsulating nucleic acids

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