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In light of these findings, it has been concluded that tobacco smoking is associated with a significantly increased risk of advanced and more severe disease in the form of pulmonary cavitation, positive sputum smear and culture results, and lower conversion rate after treatment initiation (Mahishale et al., 2015)

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An important functional difference between these conditions and G6PD deficiency is that the former result from mutations in tissue-specific genes, whereas Gd is a housekeeping gene

See the KLOW research guide for composition