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In another study, the anticonvulsant effect was found to be good or excellent when HB concentration was above 2 mM ( The brain concentrations of HB are rarely measured in the studies of neuroprotective effects of MCT (Tables 1, 2), however a few studies have looked specifically at the relationship between the plasma and brain concentrations

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By restricting excessive glycolytic flux and promoting the mitochondrial oxidation of pyruvate, cardiomyocytes achieve higher ATP production efficiency while avoiding lactate accumulation, intracellular acidification, and excessive generation of reactive oxygen species (64, 65)

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