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Vomiting Nausea Diarrhea Abdominal pain Dyspepsia Constipation Fatigue Influenza Decreased appetite Headache Sinus inflammation Diabetic retinopathy Increased lipase in the blood Dry eye Abdominal distension Gastro-esophageal reflux disease Flatulence Gastritis Urinary tract infection Consult your doctor if you experience any unusual symptoms

This study found that participants regained a significant portion of lost weight after discontinuing semaglutide: Rubino D et al., Discontinuation of GLP-1 Receptor Agonist Therapy and Weight Regain, Frontiers in Endocrinology , 2021

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28.7% 7.8%), but they experienced more severe long-term weight regain (median regain: 14.2 kg vs