glutathione for autoimmune – The #1 Nutrient Detoxification – AMMD Gut & Autoimmune Diseases Share

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Unlike direct GPX4 inhibition, which remains difficult to deploy in vivo owing to bioavailability and systemic toxicity concerns, targeting enzymes that sustain the reduced CoQ 10 (CoQ 10 H 2 , ubiquinol) pool may provide a more tractable and context-selective strategy to lower the ferroptotic threshold in tumors

Front Neurol 12:609236 Petrillo S, Pietrafusa N, Trivisano M et al (2021) Imbalance of systemic redox biomarkers in children with epilepsy: role of ferroptosis [J]