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Activation of these receptors suppresses nociceptive transmission and alters dopaminergic and stress-response signaling within the central nervous system

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Alongside the use of startle reflex Inhibition to assess tinnitus-like behavior, additional outcome measures included thresholds and wave-I amplitudes of the ABR, ribbon synapse counts in inner hair cells (IHCs) of the cochlea, and expression levels of GABA type A receptor (GABA A R) 1 subunits in the dorsal cochlear nucleus (DCN)