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17 In addition to these findings, the SUSTAIN-6 trial also showed that semaglutide can offer a significant reduction in the risk of new or worsening nephropathy including persistent macroalbuminuria, increase in serum creatinine or the need of renal replacement therapy

Last reviewed: June 24, 2026 Last updated: June 24, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Even when lifestyle changes and the semaglutide dosage schedule are followed perfectly, some people do not lose weight or stop losing weight after some time

Choose water and unsweetened drinks since sugary beverages could aggravate gas for some people

semaglutide degrades rapidly when left unrefrigerated, losing potency within hours to days depending on ambient conditions