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Replication protein A (RPA) has demonstrated its capability in DNA damage response, as well as in HR and NER DNA repair pathways, and potential chemical candidates against RPA have been shown to increase sensitivity to anti-cancer agents

doi:10.1016/j.ejogrb.2017.03.004

As a consumer representative, I worry what placing a bulk substance on the list conveys in terms of FDA approval, said committee member Todd Durham, senior vice president of clinical outcomes and research at the Foundation Fighting Blindness, who voted no on adding these peptides to the list

doi: 10.1021/acsmedchemlett.8b00466 88 YuZCFuRLiYZhaoDYJiangHHanD