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-HB exhibits potent anti-inflammatory properties, reducing pro-inflammatory cytokines and microglial activation by inhibiting pathways such as NF-B and NLRP3 inflammasome

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However, since the number of non-English articles on the associations between ASD and oxidative stress markers were very limited, and no evidence of publication bias for most analyzed oxidative stress markers, it is unlikely that this would significantly influence our meta-analysis outcome

10.1111/j.1365-2869.2012.01030.x 33 JiS.WangL.LiL

NRF2 may also improve the Blood Brain Barrier, or BBB