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None of them suppress consciousness or create artificial sedation

Current evidence positions them as metabolic support tools, not direct fat-loss agents, and results require diet and lifestyle changes alongside them

Investigation of the mechanisms underlying the beneficial metabolic effects of multi-agonist therapies, conducted in PWA mice, as a genuine model for the metabolic alterations of PCOS 36 , revealed a predominant action in terms of suppression of food intake, with negligible effects in terms of energy expenditure, thermogenic function or locomotor activity