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Description

It promotes SMAD3 activation by TGF- receptors and interacts with SMAD3 in the nucleus to regulate gene transcription (Fig

the figures above come from Lillys December 2025 press release

clinical trial registration number NCT02759107) (57)

In a study that examined the effects of GLP-1 receptor agonists (GLP-1 RAs) on liver fibrosis in type 2 diabetes (T2DM) patients with nonalcoholic fatty liver disease (NAFLD)