A 2024 Reuters analysis by Prime Therapeutics (a large PBM) reported that in the first two years after introduction, patients on weight-loss GLP-1s actually had higher total annual healthcare costs than matched controls (driven by drug costs and some medical utilization) ( [42] )
Huffman LJ, Judy DJ, Rao KM, Frazer DG, Goldsmith WT (2000) Lung responses to hypothyroidism, hyperthyroidism, and lipopolysaccharide challenge in rats
They noted that, despite the consistent lack of statistical power in the body of literature on this topic, None of the trials reported evidence of significant decreases in efficacy from antioxidant supplementation during chemotherapy
These patterns suggest that IL-24 is more closely associated with downstream effector cytokine responsesparticularly those involving IL-13 and IL-9rather than upstream regulators of T helper cell differentiation
It should also synergize well with magnesium , another GABAergic ingredient in this formula