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The blockage generates an environment where bacteria can thrive and trigger inflammatory responses

A separate open-label study of 31 patients (22 children, 9 adults) confirmed sustained improvements through 144 weeks of treatment, with median ALT decreasing by 42 U/L and LDL-cholesterol decreasing by 52.6 mg/dL

This review aims to systematically summarize the mechanistic insights and clinical advances of GLP-1with dual or triple receptor agonists in MASLD treatment, thereby promoting a more profound comprehension and facilitating their application in clinical practice (Figure 1)

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