Liver damage is a very rare side effect of the pill
Food & Drug Administration, FDA Approves New Medication for Chronic Weight Management, November 2023 6 PBS, The many ways new weight loss drugs could transform the economy, June 2024 7 MarketWatch, Obesity drugs next wave: These companies could snag 20% of GLP-1 market, analysts say, August 2024 8 The Minnesota Star Tribune, Analysis finds that after 2 years GLP-1 drugs for weight loss dont justify their price, October 2024 9 PWC, From molecules to milestones: Reinventing for the future of weight loss drugs, October 2024 10 Kaiser Family Foundation KFF Health Tracking Poll, May 2024: The Publics Use and Views of GLP-1 Drugs, Accessed: 01-13-2025 11 The Washington Post, Weight-loss drugs change shopping habits, September 2024 12 Cornell, The No-Hunger Games: How GLP-1 Medicine Adoption is Changing Consumer Food Purchases, December 2024 13 Bloomberg, Ozempic is Making People Buy Less Food, Walmart Says, October 2023

During this adaptation phase, temporary side effects including headaches may be more pronounced as the body acclimates to the drug's pharmacological actions
Since the current epidemic of end-stage liver diseases, including NAFLD, limits liver transplantation, more preclinical studies are needed to test the efficacy of drugs such as G49 and to identify new therapeutic targets
Contraindications include personal or family history of medullary thyroid carcinoma, MEN2 syndrome, severe kidney disease, acute pancreatitis, diabetic retinopathy requiring treatment, and pregnancy