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However, the comprehensive mechanisms remain to be elucidated

The most reported side effects include nausea, flushing, and headaches, which tend to be mild and short-lived

4 Clinical testing and assessment related to ferroptosis 4.1 Biomarkers 4.1.1 Definition and mechanism of ferroptosis biomarkers Ferroptosis, as a novel form of programmed cell death, involves complex mechanisms and multiple biomolecules and metabolic pathways (54, 55)

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The shRNA sequence (TRCN0000322995) targeting ATG10 was designed according to MISSION shRNA Plasmid DNA (MERCK) and synthesized and joined the FastDigest BshTI/FastDigest EcoRI linearized (Thermo Fisher) pLKO.1-GST DAF vector with T4 DNA ligase (EL0011, Thermo Fisher)