In other words, coffee may be literally rewiring our genetic expression to slow down aging at the cellular level, potentially extending healthspan, and consistent, robust scientific evidence does show regular coffee drinkers do actually live longer, and not only that, they also experience lower rates of the deadliest chronic diseases like heart disease, diabetes, and even certain cancers
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It may be important to include measurements of biomarkers of oxidative damage (e.g., products of DNA and lipid oxidation, such as 8-hydroxy-2-deoxyguanosine, 8-OHdG, or F 2 -isoprostanes) in observational studies, suggesting that the therapeutic benefit may actually be associated with an antioxidant effect (Moosmann and Behl, 2002
10.1186/s12870-020-02443-y BMC Plant Biol
