better than semaglutide vs Tirzepatide: Is Tirzepatide Better? Tirzepatide vs Semaglutide: 2025 NEJM

This compound works by mimicking the action of the GLP-1 hormone, which is vital for appetite regulation and insulin secretion

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Clinical trials suggest tirzepatide produces greater average weight loss (up to 22.5%) compared to semaglutide (up to 14.9%), though individual responses vary and both medications are considered highly effective

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Additionally, among SASP factors, there are growth factors such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and insulin-like growth factor 1 (IGF-1), which, when secreted into the environment by senescence cells, stimulate the repair and regeneration of surrounding tissues [13]