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The NICE clinical guideline on the identification, assessment and management of obesity recognises GLP-1 receptor agonists, including semaglutide, as clinically appropriate interventions for adults who meet the relevant eligibility criteria, and emphasises that clinical outcomes are achieved when treatment is delivered as intended including strict adherence to administration protocols such as the fasted dosing requirement

Placebo groups showed minimal change

Some of the most common for semaglutide include: nausea vomiting diarrhoea stomach pain constipation A change in vision is listed as one of the more serious potential side-effects, on both Ozempic and Wegovy's safety information for patients

doi: 10.3390/antiox9111082 173 LiHMinJChenYLiHZhangY