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Because the magnitude of weight loss drives most of the sexual-function benefit through hormonal and vascular pathways, retatrutide's Phase 2 results suggest it may produce larger hormonal improvements than semaglutide, and comparable or modestly greater improvements than tirzepatide

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BPC-157 (Body Protection Compound-157), also designated as PL 14736, is a synthetic pentadecapeptide composed of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) that was first isolated and identified from human gastric juice in the early 1990s