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Importantly, this is a proposed rationale, not a settled clinical fact

Inform your doctor if you have any of the following pre-existing medical conditions, as they may affect whether Tradjenta is right for you: Pancreatitis Severe joint pain Heart failure Drug Interactions: Before taking Tradjenta, it is essential to discuss all potential risks and interactions with your doctor or pharmacist

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Maintenance of weight loss: once therapeutic levels have helped patients achieve their goal weight, lowering the dose may be a helpful longer-term way of keeping them there