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In laboratory and pre-clinical research settings, glutathione is studied across virtually every area of cellular biology owing to its central, non-redundant role in redox homeostasis and its interactions with dozens of enzyme systems, signalling pathways, and disease-relevant biological processes

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A novel intestinal-specific inhibitor of MTP has been shown to ameliorate impaired glucose and lipid metabolism in Zucker diabetic fatty rats, but whether this effect was due to impairment of food intake or to inhibition of fat absorption is not clear [82]

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To further validate the specificity of the kinase inhibitors we analyzed known substrates of the individual kinases and found good reproducibility in our dataset (Fig

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