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Schedule: Weekly subcutaneous injections for 1216 weeks (or longer as appropriate)

CJC-1295 also stimulates IGF-1 (Insulin-like Growth Factor-1) secretion by the liver, the primary mediator of the anabolic and metabolic effects of GH

5 (download XLSX Source data for Extended Data Fig

Although our results are promising with regard to the maintenance of disc height and biomechanical properties in early stages of disease, further long-term in vivo studies will be required to assess clinical translation, particularly in the aspects of reducing low back pain associated with chronic IDD