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This study is of particular interest because the researchers also paired gene studies with laboratory studies, confirming that changes in gene expression are associated with improved collagen reorganization and fibroblasts function [ 28 ] Further studies confirmed the ability of GHK-Cu to reverse gene expression in COPD back to health [ 29 ]

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Namely, KEAP1 is a redox biosensor utilizing reactivity of sulfur atoms, switching on the NRF2-mediated transcriptional activation of cytoprotective genes in response to the redox disturbance