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Recently, vinca alkaloids have demonstrated to exert their neurotoxicity via activation of spinal cord glia (i.e., astrocytes and microglia), offering an option for the treatment of CIPN through pharmacological antagonism of this phenomenon

This consultation confirms that disease activity is stable, current DMT regimens are working effectively, and the patient has no contraindications such as severe nutritional deficiency, swallowing disorders, or active disease relapse

it did not randomize participants against the injectable 2.4 mg formulation in the same trial

Studies on frog Trypanosomiasis

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