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Put another way, if the tertiary structures of two molecules (or supramolecular aggregates) resemble each other closely enough to fool an antibody into cross-reacting, then by the same token such a similarity could prompt an endogenous brain protein into being cross-seeded and templated by an exogenous prion-like element

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What this means for DFU care: Their anti-inflammatory, vascular, and neuroprotective properties could make GLP-1 receptor agonists a valuable adjunctive therapy in managing complex, chronic diabetic foot ulcers a hypothesis worth further exploration

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