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Moreover, glutaminase2 (GLS2), cytochrome c oxidase 2 (SCO2) and several noncoding RNAs were confirmed to be the target molecules of p53-mediated ferroptosis [44, 45]

Concurrently, an analysis predicated on two markers of T-cell activation, CD69 and CD25, revealed a substantial augmentation in the proportion of activated CD8 T cells within the tumor, along with a notable escalation in the concentration of cytokines in the interstitial fluid of the tumor

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Acknowledgements This research was conducted at the University of Delaware and funded by MSMs startup fund from the University of Delaware