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doi: 10.3389/fmicb.2015.00587 [DOI] [PMC free article] [PubMed] [Google Scholar] 33.Yasufuku T, Shigemura K, Shirakawa T, et al

The cAMP accumulation was measured using a cAMP Gs Dynamic Kit (Cisbio) and EnVision reader (PerkinElmer)

This is generally reversible and not harmful, but it requires baseline measurement and periodic monitoring to distinguish normal metabolic adjustment from true thyroid dysfunction