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In our study, as the intracellular -GC level was only increased slightly compared with that of original strain W303-1b when F pathway was introduced, we artificially introduced a flexible six-glycine linker between the two enzymes of G pathway as well as P pathway to improve the coupling efficiency by mimicking the native domain fusion of GshF

advanced endometriosis is associated with adhesions and altered pelvic anatomy that can impair the movement of oocytes and sperm, induce uterine dysfunction, and prevent normal fertilization and embryonic development