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Innate immunity in Alzheimers disease

CYP1A1 metabolic activity has also been shown to be increased by approximately 66%70% in smokers, mainly due to exposure to aryl hydrocarbons such as benzo [a]pyrene (Vistisen, Loft, and Poulsen, 1991)

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Inflammaging is associated with increased susceptibility to infections, autoimmune disorders and various age-related diseases, creating a feedback loop that accelerates the breakdown of immune health and increases morbidity and mortality risks among elderly [3, 4]