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Frontiers in Endocrinology, 9 , 246

It works by activating downstream biological processes such as: Receptor activation Growth factor upregulation Angiogenesis Cellular signaling cascades These processes continue for weeks after the peptide itself has been cleared from circulation

This is not a routine test, but it is on my radar for specific patients whose B12 deficiency is severe or does not respond as expected to supplementation

The historical perspective Initial clinical findings that the intestinal epithelium of IBD patients is more permeable to tracer molecules known to permeate through the paracellular space 28, 29, 30, 31 led to the hypothesis that an uncontrolled mucosal barrier may help promote IBD pathogenesis

Case in point, I had a young athlete that came to me the other day and I just asked him a very quick question