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In both men and women, obesity can disrupt normal reproductive hormone signaling, impair fertility, and negatively affect reproductive outcomes

It also interacts with melanocortin receptors, particularly MC1R, which are expressed on immune cells including macrophages, dendritic cells, and T cells

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Start your intake Why Generic Weight Loss Calculators Fall Short for GLP-1 Medications Most weight loss calculators assume linear metabolic response and ignore biological heterogeneity