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Despite this, they did not investigate how hypocarnitinemia impacted the efficacy of diet therapy

Inhibition of protein translation restored both mTORC1 signaling and the ISR during cystine starvation, suggesting the bulk of cellular cysteine was committed to the biosynthetic process

doi: 10.1111/J.1398-9995.2009.02220.X 225 HollamsEMHartPHHoltBJSerralhaMParsonsFde KlerkNHet al

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Then, a fermentation experiment in Erlenmeyer flasks was performed using the G3-SF strain (containing Sc GSH1, Sc GSH2, St GshF, and Sc ADK1), with the highest GSH titer and yield of 999.33 47.26 mg/L and 91.53 4.70 mg/g, respectively