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Phase 1 human trials have been registered in some geographies Published human efficacy data at the level of a completed, results-reported phase 2 study are not yet a settled part of the dataset Commercial development is active but has not produced a near-term approval path Patients and clinicians tracking 5-amino-1MQ should monitor ClinicalTrials.gov and peer-reviewed publications for current status

Juan Francisco Merino-Torres: provided expert clinical opinion and critical revision of the manuscript for important intellectual content

The concentration of each drug solution was adjusted to maintain the dosing volume at 0.5 mL/kg

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3 (download XLSX Statistical Source Data for Fig