A peptide is a small chain of amino acids, which are the building blocks of proteins in the body
In cisplatin-induced AKI, SS-31 may exert antioxidative stress and antiapoptotic effects by modulating mtROS production, downregulating the NLRP3-IL-1 /caspase 1 signaling pathway, ameliorating cisplatin-induced acute tubular necrosis, and reducing Scr and blood urea nitrogen (BUN), but not body weight, renal weight, serum albumin, and triglycerides [37]
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The mitochondria play a critical role in energy production in each cell, earning them the name powerhouses of the cell