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160 In another animal study, one group of mice were given toxic heavy metals (lead, mercury, cadmium, and copper) in their drinking water for seven weeks, while another group underwent the same treatment but, in addition, received vitamin E five times weekly
Short-term tolvaptan increases water intake and effectively decreases urinary calcium oxalate, calcium phosphate and uric acid supersaturations
doi:10.1021/acs.jmedchem.1c00565 Eren S, Tonin G, Jurii Eren D, Klen J
That 11 percent difference compounds with every dose