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10.2174/13816128130111 128 SikiricP.SeparovicJ.AnicT.BuljatG.MikusD.SeiwerthS.et al (1999a)

Food intake over the circadian cycle was unaffected by neuronal ablation in either sex (Extended Data 1bc, kl), and there was no effect on meal size, frequency or duration (Extended Data 1eg)

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The analysis on the respective cohorts was based on the following safety outcomes over 5 years from drug initiation: DKA, hypoglycaemia requiring admission to secondary care, urinary tract infection (UTI), pyelonephritis, candidiasis of the lower genital tract, acute pancreatitis and gastrointestinal upset