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It works by mimicking the hormone GLP-1, which helps regulate appetite, slows gastric emptying, and promotes insulin release

Injectable use should only be handled by qualified medical professionals in a clinical setting

The incidence of gastrointestinal adverse events was similar when comparing tirzepatide with GLP-1 RAs

Plasma or serum concentration of pyridoxal 5-phosphate (PLP) is commonly used to assess vitamin B 6 nutritional status, with concentrations below 30 nmol/L often recognized as inadequate and concentrations below 20 nmol/L considered deficient (13, 14)

Nevertheless, numerous ongoing trials are investigating the cardiometabolic effects of GLP-1RAs in patients with mental illness, especially for those on antipsychotics (Supplementary Section 3)such research should therefore address the abovementioned knowledge gap