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Glucagon-like peptide-1 and the central/peripheral nervous system: Crosstalk in diabetes

Clinical trials are already underway to explore their full potential in treating conditions beyond depression, such as PTSD, anxiety, and chronic stress

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It is commonly referenced in laboratory and preclinical research examining melanocortin receptor activity, peptide signalling pathways, and central nervous systemrelated mechanisms within controlled research systems

The evidence base is overwhelmingly preclinical, and there are no completed, published Phase 2 or 3 human efficacy trials only early-stage safety work [9]