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These results remain significant when controlling for comorbidities such as T2DM

Orally Gastrointestinal discomfort, allergic reactions, worsening of asthma, toxicity, and interference with other medications

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Much of the available literature has focused on the protective effects of aerobic exercise and cardiorespiratory fitness in reducing the onset and progression of ADRD (Erickson and Kramer, 2009