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Podolsky, M

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et al., provide evidence that in patients with T2DM, SGLT-2 inhibitors significantly reduce, though to different extents, visceral adipose tissue, subcutaneous adipose tissue, and ectopic liver fat

According to the FDA's approval, the eligibility criteria are as follows: For Adults: A Body Mass Index (BMI) of 30 kg/m or greater (defined as obesity), OR a BMI of 27 kg/m or greater (defined as overweight) with at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol