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GSH is an essential antioxidant against reactive oxygen and nitrogen species and is critical in regulating mitochondrial function, maintaining cell redox homeostasis, cell cycle regulation, apoptosis, immunological defense, and modulating pathological abnormalities (45, 46)

The article suggested that the concentration of endogenous N/OFQ, although elevated in asthma, is too low to modulate the immune system and AHR [43]