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As a result, there has been increasing interest in imaging strategies that move beyond structural assessment to capture functional and molecular features of tumour physiology in vivo

This parameter has been further studied, showing that those men and women in the lowest quartile of the IGF-1/IGFBP3 ratio are threefold more likely to meet the Adult Treatment Panel III (ATP-III) definition for MetS, and twice as likely to be insulin resistantthat IGF-1/IGFBP-3 ratio decreases notably as the number of MetS components increases [217]

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